Fitness and Health

Virus Tamed To Destroy Cancer Cells But Leave Healthy Cells Unharmed

Posted by admin on May 27, 2009
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ScienceDaily (May 25, 2009) — Scientists at Oxford University have tamed a virus so that it attacks and destroys cancer cells but does not harm healthy cells.  They determined how to produce replication-competent viruses with key toxicities removed, providing a new platform for development of improved cancer treatments and better vaccines for a broad range of viral diseases.

A common type of virus has been modified to attack cancer cells without harming healthy cells. (Credit: Copyright Oxford University)

Cellular microRNA molecules regulate the stability of mRNA in different cell types, and this newly-understood mechanism provides the possibility to engineer viruses for cell-specific inactivation. Cancer Research UK scientists at the University of Oxford, United Kingdom, with support from colleagues at Vrije Universiteit, Amsterdam, report that this approach can be used to regulate proliferation of adenovirus.

Adenovirus is a DNA virus widely used in cancer therapy but which causes hepatic disease in mice. Professor Len Seymour and colleagues found that introducing sites into the virus genome that are recognized by microRNA 122 leads to hepatic degradation of important viral mRNA, thereby diminishing the virus’ ability to adversely affect the liver, while maintaining its ability to replicate in and kill tumor cells.

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The Healthiest Foods on Earth

Posted by admin on May 22, 2009
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Pineapple Speeds post-surgery Promotes joint health Reduces asthma inflammation
Blueberries Restore antioxidant levels Reverse age-related brain decline Prevent urinary tract infection
Spinach Helps maintain mental sharpness Reduces the risk of cancers of the liver, ovaries, colon and prostate Top nutrient density
Red Bell Pepper Reduces risk of lung, prostate, ovarian and cervical cancer Protects against sunburn Promotes heart health
Broccoli Reduces diabetic damage Lowers risk of prostate, bladder, colon, pancreatic, gastric and breast cancer Protects the brain in event of injury
Tomato Reduces inflammation Lowers risk of developing esophageal, stomach, colorectal, lung and pancreatic cancer Reduces cardiovascular disease risk
Apple Supports immunity Fights lung and prostate cancer Lowers Alzheimer’s risk
Artichoke Helps blood clotting Antioxidant Superfood Lowers “bad” cholesterol
Arugula Lowers birth defect risk Reduces fracture risk Protects eye health
Asparagus Nourishes good gut bacteria Protects against birth defects Promotes heart health
Avocado Limits liver damage Reduces oral cancer risk Lowers cholesterol levels
Blackberries Build bone density Suppress appetite Enhance fat burning

Butternut Squash
Supports night vision Combats wrinkles Promotes heart health
Cantaloupe Bolsters immunity Protects skin against sunburn Reduces inflammation
Carrot Antioxidants defend DNA Fights cataracts Protects against some cancers
Cauliflower Stimulates detoxification
Suppresses breast cancer cell growth
Defends against prostate cancer
Cherries Alleviate arthritic pain and gout Lower “bad” cholesterol Reduce inflammation
Cranberries Alleviate prostate pain Fight lung, colon and leukemia cancer cells Prevent urinary tract infection

Green Cabbage
Promotes healthy blood clotting Reduces risk of prostate, colon, breast and ovarian cancers Activates the body’s natural detoxification systems
Kale Counters harmful estrogens that can feed cancer Protects eyes against sun damage and cataracts Increases bone density
Kiwi Combats wrinkles Lowers blood clot risk and reduces blood lipids Counters constipation
Mango Supports immunity Lowers “bad” cholesterol Regulates homocysteine to protect arteries
Mushrooms Promote natural detoxification Reduce the risk of colon and prostate cancer Lower blood pressure

Orange
Reduces levels of “bad” cholesterol Lowers risk of cancers of the mouth, throat, breast and stomach, and childhood leukemia Pectin suppresses appetite
Papaya Enzymes aid digestion Reduces risk of lung cancer Enhances fat burning
Plums & Prunes Counter constipation Antioxidants defend against DNA damage Protects against post-menopausal bone loss

Pomegranate
Enhances sunscreen protection Lowers “bad” cholesterol Fights prostate cancer

Pumpkin
Protects joints against polyarthritis Lowers lung and prostate cancer risk Reduces inflammation
Raspberries Inhibit growth of oral, breast, colon and prostate cancers Antioxidant DNA defense Lower “bad” cholesterol levels

Strawberries
Protect against Alzheimer’s Reduce “bad” cholesterol Suppress growth of colon, prostate and oral cancer

Sweet Potato
Reduces stroke risk Lowers cancer risk Protect against blindness
Watermelon Supports male fertility Reduces risk of several cancers: prostate, ovarian, cervical, oral and pharyngeal Protects skin against sunburn
Banana Increases Fat Burning Lowers risk of colorectal and kidney cancer, leukemia Reduces asthmas symptoms in children

 

Source: http://www.huffingtonpost.com

What Do Really Nurses Do?

Posted by admin on February 23, 2009
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Suzanne Gordon

Topics in Advanced Practice Nursing eJournal.  2006;6(1) (c)2006

A Vow of Silence?


Several weeks ago, I was invited to speak to a group of undergraduate students who had been asked to read my new book, Nursing Against the Odds, for their history of science class at Harvard University. During the hour-and-a-half discussion, one question that kept popping up was: “What do nurses really do?” As I left the room, I pondered, as I often do, why the public has so little understanding of the consequential nature of nursing practice. Clearly, it’s because of traditional stereotypes about nursing. But it’s also because nurses have been socialized to be silent about their work or to talk about it in ways that fail to reverse these traditional stereotypes.

When I ask nurses to describe their work, many respond: “Oh it’s too hard to talk about. It’s too diffuse, too vague, too indefinable.” But I have written thousands of pages about nursing and I am not a writer of fiction. I’ve been able to write about nursing because I’ve observed nurses at work and asked them a lot of questions about their practice.

What Nurses Do.

Here is what I think nurses do.   Using their considerable knowledge, they protect patients from the risks and consequences of illness, disability, and infirmity, as well as from the risks and consequences of the treatment of illness. They also protect patients from the risks that occur when illness and vulnerability make it difficult, impossible, or even lethal for patients to perform the activities of daily living — ordinary acts like breathing, turning, going to the toilet, coughing, or swallowing.

Even the most emotional work nurses do is a form of rescue. When nurses construct a relationship with patients or their families, they are rescuing patients from social isolation, terror, or the stigma of illness or helping family members cope with their loved ones’ illnesses.

What do nurses do? They save lives, prevent complications, prevent suffering, and save money.

Why do nurses have a hard time explaining such compelling facts and acts? Sioban Nelson and I have argued in a recent article in the American Journal of Nursing,[1] it’s because they’ve been educated and socialized to focus on their virtues rather than their knowledge and their concrete everyday practice.   They’ve been taught to wear their hearts and not their brains on their sleeves as they memorize and then rehearse the virtue script of modern nursing.

If you analyze the words and images of campaigns used to recruit nurses into the profession or listen carefully to the stories nurses tell about their work, nurses may not use the available research to fully explain why what they do is so critical to patient outcomes.   Although many studies, conducted by nursing, medical, and public health researchers, have documented the links between nursing care and lower rates of nosocomial infections, falls, pressure ulcers, deep vein thrombosis, pulmonary embolism, and deaths, most promotional campaigns and many stories nurses themselves tell about their work ignore these data.

Instead, nurses focus on their honesty and trustworthiness, their holism and humanism, their compassion, and their caring.  The problem is that when they focus on caring, they often sentimentalize and trivialize the complex skills they must acquire through education and experience.  They often fail to explain that caring is a learned skill and not simply a result of hormones or individual inclination.   After all, knowing when to talk to a patient about a difficult issue, when to provide sensitive information, when to move in close to hold a hand or move away at a respectful distance all are complex decisions a nurse makes.   To make these decisions, nurses use equally complex skills and knowledge they have mastered. But all too often nurses make these skills and knowledge invisible or describe nursing practice in terms that are far too limited.

Nurses are still talking about themselves — or allowing themselves to be talked about — in the most highly gendered, almost religious terms and allowing themselves to be portrayed with the most highly gendered, almost religious images.   Indeed, as Nelson and I argue, with the best intentions in the world, many modern nursing organizations and nurses reproduce and reinforce traditional images of nursing as self-sacrificing, devotional, altruistic, anonymous, and silent work.[1] Just think of one of the jingles in the recent Johnson & Johnson image campaign:

You’re always there when someone needs you
You work your magic quietly
You’re not in it for the glory
The care you give comes naturally.

Historical Images of Nursing and Nurses.

Unfortunately, like those above, many of the images and words nurses mobilize reflect the religious origins of the profession. Nurses in religious orders were socialized to sacrifice every shred of their individual identity, to be obedient members of an anonymous mass. Religious nurses were taught not to claim credit for their work and accomplishments but were instead supposed to view themselves as divine instruments who willingly assigned the credit for their accomplishments to God, the Bishop, the Abbot, or the Mother Superior.

Most importantly, these images reflect a time when nurses were taught to Say Little and Do Much because to talk about a good deed was to turn it into a bad one — to exhibit the sin of pride.   What nurses could accept were compliments for their deferential behavior and angelic virtues.   What they  could talk about was self-sacrifice and devotion and the outside agents they served.

If you look closely at the history of the problem of nursing visibility, you see that this religious depiction of nursing was not only a relic of the origins of nursing in Christian penitential practice but was also a legacy of the 19th century movement to professionalize nursing.   In the 19th century, religious and social reformers like  Florence Nightingale adapted the religious template to help women who wanted and/or needed to work outside of the home find purposeful paid work.   In a society where gender roles were very rigid and people prized modesty and innocence, reformers needed to make it safe for female nurses to work in public spaces with strangers — mostly strange men.

Nurse reformers helped respectable women affect this passage by borrowing religious images, costumes, language, and metaphors. The nun’s cornette was transformed into the nurse’s cap.   In English-speaking countries, nurses were called “sisters.”

Nurse reformers tried to desexualize nurses just as nuns (women who weren’t really women) had been desexualized before them.   Nursing students wore ugly uniforms, were not allowed to marry, and were sheltered in cloister-like dormitories in or near the hospital.   Nurses were said to be self-sacrificing and morally superior and would thus create order out of the chaos of the 19th century hospital.

Focusing on nurses’ virtues also helped nurses in their long battle with medicine for what became, in the 19th century, the highly contested terrain of the hospital.    Before the 19th century, very few doctors had ever set foot in a hospital. In the 19th century, scientifically oriented doctors were moving into the hospital in greater numbers and wanted to control the hospital.   They were not pleased to see a group of women who wanted authority and education competing for a sphere of influence (even a separate female sphere) inside the hospital.

Doctors were happy to have trained nurses but only if they were their servants. They wanted nurses to know what to do and how to do it but not why they were doing it.   They didn’t want anyone to know if a nurse had acquired scientific, medical, or technical mastery.   Because nursing at this time was feminized, women with no political, legal, economic, or social power had to make a deal with medicine, and the deal was that nurses could have virtues but not knowledge.

In the 19th century, nursing was thus constructed as self-sacrificing, anonymous, devotional, altruistic work.   While this was a functional bargain to make over a century ago, this template reigns today in spite of the fact that things have changed dramatically for women — which is why it’s time for a change.

Now Is the Time for Change

I believe the public knows that nurses are kind, caring, and compassionate and that they provide patients with more information than doctors do. People don’t know, however, that nurses have medical knowledge, participate in medical cures, and have technological know-how. I believe nurses can advance knowledge of their profession if they amplify their caring stories and include anecdotes that help us understand that doctors don’t do all the curing.

The public needs to know that nurses — regular, ordinary bedside nurses, not just nurse practitioners or advanced practice nurses — are constantly participating in the act of medical diagnosis, prescription, and treatment and thus make a real difference in medical outcomes.   Nurses can help the public understand that nursing is a package of medical, technical, caring, nursing know-how — that nurses save lives, prevent suffering, and save money. If nurses wear not only their hearts, but also their brains on their sleeves, perhaps the public, like those students at Harvard, will finally understand what nurses know and do.

References

1.      Gordon S, Nelson S. An end to angels. Am J Nurs. 2005;105:62-69.

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Safe Harbor Peer Review

Posted by admin on February 16, 2009
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“Safe Harbor” (”Request for Peer Review”) can only apply to nurses in both staff and supervisory positions when the nurse believes an assignment may place patients at risk of  harm, thus violating the nurse’s duty to the patient.  Safe Harbor provides a means by which a nurse can protect his/her nursing license from board action as well as have nursing peers in the same practice setting review the requested assignment.  New Incident-based (Rule 217.19) and Safe Harbor (217.20) peer review rules.  Nursing associations that represent LVNs, RNs and advanced practice nurses as members may also have information about Safe harbor Peer Review for their members and other nurses.

The BON has no authority over employment issues, but nurses does have a civil recourse in matters where nurse’s decision to invoke Safe harbor was made in “good faith”, but negative employment action occured as a result of the nurse request.  A nurse also has a “whistleblower” protections when the nurse reports a facility, physician, or other entity for violations of laws relating to patient care and/or illegal acts, such as fraud  [ NPA 301.4025, rule 217.20(i)]

Become familiar with the laws that govern your nursing practice.  A sound knowledge base regarding the rules and statutes will help your protect your patients as well as your nursing practice.

For inquiries to the Texas Board of Nursing e mail your questions  or inquiries to webmasters@bon.state.tx.us or visit the Frequently Asked Questions Section of the Board’s web site (http://www.bon.state.tx.us/olv/faqs-licensing.html)

This is a reprint from Texas Board of Nursing Bulletin, vol 39, No 4, p.9

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EKG Review Site

Posted by admin on February 16, 2009
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Here is a good site I found for EKG review.  If you go to the Table of Contents page, scroll down and you will find the rhythms to click on and then it will show you the strip, the identification criteria, causes and treatment.  If you can not pull it up for a reason, please let me know.

Link:  http://www.rnceus.com/course_left.asp?exam_id=16

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